Androcell 2G

Male Sexual Function Regulator.
Hormone Cycle Activator and Precursor

The organic physical condition called Androgen Deficiency in the Ageing Male (ADAM), also known as male menopause, represented by the physiological diminishment of the hormone system and other vital male functions, is known as andropause.

The most common symptoms of andropause are: (as instructed).

Due to the rise in the male population worldwide affected in the last few decades, the projections of the European Sexual Medicine Society show the likelihood that andropause will continuing rising proportionately due to bad habits, such as: stress, lifestyle, poor nutrition, diseases, genetics, amongst others.

Approximately 30% of males between the ages of 40 and 50, and 70% of males age 60 and older, present and experience changes with the decrease or partial or total loss of some functions and conditions inherent to the individual. There is a reduced production of sex hormones by the suprarenal gland with weak androgenic effect, testicular atrophy, as well as reduced function of Leydig (testosterone-producing) cells and of the sensitivity of the hypothalamic-hypophiseal axis. There is a diminished production of melatonin, related to sleep and circadian rhythm disorders, and of the growth hormone related to reduced muscle mass. There is an increase in the production of sex hormone fixing proteins, which reduces the concentration of biologically active testosterone, as well as diminished libido, erectile dysfunction, changes in the skin, reduced bone mineral density, and vasomotor symptoms.

With the knowledge that, after age 40, testosterone levels start decreasing, this is indicative, per se, of a physiological situation that precedes, to a lesser degree, symptoms of andropause.

Andropause should be viewed like any other stage in life, not as a permanent state. Thus, the follow-up to any treatment is very important to evaluate its effectiveness on levels, in order to verify that the optimum hormone balance that the patient needs is maintained. Specialists recommend consulting a doctor at the first symptoms of andropause, to know all the therapeutic alternatives available to improve the quality of life during this stage.

For the scientists of the Biocell Ultravital Bioresearch Institute, prevention represents the most important mission in the treatment of pre-andropause; likewise, it should be seen as the main treatment alternative to prevent a premature loss of functions and the after effects of greater harm.

Androcell 2G is an oral pharmaceutical supplement of the highest quality, covered by an exclusive international patent in which we have combined natural and biological factors in a single formula, so that all the components, acting synergistically, intervene in a man's endocrine and regenerative systems, helping to provide an improvement of symptoms step by step until stabilising them, by restoring the patient's vitality and longevity of years past. In addition to recovering and normalising functions, it will also effectively protect against the proliferation of related diseases, by stimulating the hormone cycle, revitalising cell function and activating the natural production of testosterone lost with the passing of the years.

CLINICAL INFORMATION AND PHARMACOLOGY

COMPOSITION:

Each 500-mg capsule of Androcell 2G contains:
Testicle Cell Extract, Passiflora Incarnata Flower Extract, Piper Nigrum Extract, Urtica Dioica Extract, Pregnenolone, Maca (Lepidium Meyenii Walp), Ptychopetalum Olacoïdes Extract, Zinc Gluconate, Zingiber Officinale Root Extract, Lactoferrin, Maltodextrin, Citrullus Vulgaris Fruit Extract.

Mechanisms of Action

The Androcell 2G formula acts in complete synergy, increasing and activating all the mechanisms of the body's sexual and hormonal systems, converting testosterone into dihydrotestosterone (DHT) which, in turn, increases the production of red blood cells (erythropoiesis) and of hemoglobin, with the consequent increase in the transport of oxygen. The testicle cell extracts boost the action, inducing the changes necessary to reactivate testicle- and Sertoli-germ cells, increasing spermatogonia, spermatocytes and spermatids without altering the seminiferous tubules, regulating the body's hormonal balance without exceeding physiological limits, but increasing key hormone blood levels while slowly correcting functional disorders and the progressive increase in sexual desire and potency, as well as a positive control on the male reproductive system. The biological factors boost the rest of the components, since they act mainly as specific regulators through the cells in the formula, increasing the system's regenerating capacity by introducing cellular differentiation, as well as avoiding the progressive wear on the surrounding tissues.

PHARMACOKINETICS AND PHARMACODYNAMICS

Some components are absorbed by the gastric walls and others by the intestine. Passing to the liver through the lymphatic system, wherefore it is active when taken by mouth, it passes from there to the peripheral circulation where it appears in the plasma joined mainly to kilomicrons; the rest is associated with lipoproteins. A variable quantity of the amount absorbed enters the portal system and is metabolised in the liver. Some insignificant increases in plasma levels occur at a peak of 2 to 4 hours afterwards, and decline to the baseline within 8 to 12 hours. Variation between the plasma levels reached and their time spans are different in some cases, with very few variations. The cell extract components are absorbed by the macrophages and, from there, they are metabolised and transported by mitochondrial self-evaluation to the intracellular fluid which is transmitted to the surrounding cell organisms of the reproductive system. However, there are reports in which no modifications or changes have been noted in the desired direction, without any important consequence. No changes are observed in the LH and FSH plasma levels in normal patients. The restoration of testosterone to normal levels is associated with a significant improvement in feelings of well-being.
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Indications:
Androcell 2G has proven to be extremely effective in alleviating the symptoms experienced during andropause. Androcell 2G is recognised as one of the first natural products developed in Switzerland, specifically for men's health.
Principal use of Androcell 2G in the following cases:

Facilitates an increase in testosterone, DHEA and oestradiol
Increases sperm quantity and motility
Lack of energy (Physical Asthenia)
Anxiety, Nervousness, Irritability
Stimulates LH in males
Helps in sterility treatments
Improves sexual desire and potency
Trastornos del sueño
Hiperplasia Prostática Benigna

Dosage:

In Severe Advanced Andropause:
Take 4 capsules in the morning and 4 in the evening, half an hour before meals, with still (non-sparkling) water. Preferably, therapy should be started together with a complete treatment with Revercell, for 6 months.

Moderate Andropause:
Take 3 capsules in the morning and 3 in the evening, half an hour before meals, with still (non-sparkling) water, on an ongoing basis or for however long the doctor suggests.
Androcell 2G may be taken indefinitely since it is totally natural and its components do not create deposits.

Slight Andropause:
Take 2 capsules in the morning, half an hour before meals, with still (non-sparkling) water, for 3 months or for however long the doctor suggests.

In Preventive Medicine:
Take 1 capsule in the morning and another in the evening, half an hour before meals, with still (non-sparking) water, for 3 months.

Contraindications:

Androcell 2G, whereas it is an essentially natural product, does not produce any reaction at all. When taking a clinical history, one should always ask about any history of allergies, especially to one of the components of the formula.

Analysis:
A questionnaire was prepared and suggested with the following content
For patients:

Tired? Depressed? Are you feeling decreased libido? Are you lacking energy? Have your strength and endurance diminished? Have you lost weight? Do you feel less zest for life? Are you sad or ill-humoured? Do you have fewer erections? Have you noticed a recent decrease in your sports abilities? Do you suffer from drowsiness? Have you noticed a recent drop in your work output?

Patients' most frequently asked question:
Can andropause be prevented?

A Hormone Analysis can be decisive in evaluating the patient clinically and individually, but it is important to recall that only doctors, and especially endocrinologists, can issue in the end the best response and recommend accurate solutions to each patient.

However, in response to the experience and debate surrounding andropause, the European Sexual Medicine Society concluded that it can be prevented and that the appearance of the systems can be extended over time. The best scenario would be to take precautions and corrective actions to help the body reverse or delay it, by natural means, minimizing the evolution of the problem.

Can I change or improve some of these symptoms?

At present, there are countless hormone replacement products of chemical origin, with some risks and advantages, that can help.

Androcell 2G is indicated mainly to prevent the symptoms of male organic ageing, attenuating and helping to restore sexual, hormone, cognitive and organic function, thus increasing zest for life, maintaining and extending physical vigour and intellectual capacity in a healthy context, inducing the body to make its own changes and corrections for full function in the adult male.

CLINICAL STUDIES.

Clinical Studies regarding Increased Libido and Sexual Performance.

The effect of Androcell 2G on sexual desire and the lack of relationship to serum testosterone levels in healthy adult males.

This study took place over a period of 12 weeks, with a parallel trial, using the randomised controlled double blind method, in which treatment with different doses of Androcell 2G was compared to the placebo. This study wished to demonstrate whether the effect of Androcell 2G on the subjective report was related to effects on humour and serum testosterone levels.

Males between 45 and 55 years of age received Androcell 2G on one of two doses: 1000 mg or 3000 mg; or placebo. Personal perception regarding sexual desire, as well as the results of the Hamilton depression scale and the Hamilton anxiety scale, were evaluated at 4, 8 and 12 weeks of treatment. An improvement in sexual desire was detected at 8 weeks of treatment. There was no difference in the levels of serum testosterone and oestradiol in males treated with Androcell 2G and those treated with a placebo (P=NS).

The logistic regression analysis showed that Androcell 2G has an independent effect on sexual desire at 8 and at 12 weeks of treatment and that these changes are not owing to the results of the Hamilton depression and anxiety scales or to the serum testosterone and oestradiol levels. In conclusión, treatment with Androcell 2G increases sexual desire.

Effect of Androcell 2G on increased fertility and on reproductive hormone levels in helathy adult males.
This parallel trial, double blind, placebo-controlled study, in which active treatment was carried out with different doses of Androcell 2G, was compared with the placebo. The objective of the study was to prove the effectiveness that the Androcell 2G organic biofactor has on serum reproductive hormone levels in apparently healthy males, when it is administered in doses used for therapeutic purposes to increase fertility. Males between 45 and 55 years of age received 1000 mg or 3000 mg of Androcell 2G. The serum levels of luteinising hormone, the hormone that stimulates the follicles, prolactin, 17-alpha hydroxy progesterone, testosterone and 17-beta oestradiol, were measured before and after 2, 4, 8 and 12 weeks of treatment with a placebo and with Androcell 2G. The results data showed that Androcell 2G had a significant increase over the minimum and maximum references of the hormones studied and that low testosterone levels increase. The multiple regression analysis showed that serum testosterone levels were affected by treatment with Androcell 2G; as of the fourth week of the study, changes began to be noticed in comparison to the individuals who did not receive the treatment. In conclusion, treatment with Androcell 2G increases serum reproductive hormone levels.

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